USP7: NOVEL DRUG TARGET IN CANCER THERAPY

USP7: Novel Drug Target in Cancer Therapy

Ubiquitin specific protease 7 (USP7) is one of the deubiquitinating enzymes (DUB) that erases ubiquitin and protects substrate protein from degradation.Full activity of USP7 requires the C-terminal Ub-like domains fold back onto the catalytic domain, allowing the remodeling of the active site to a catalytically competent state by the C-terminal pep

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Saint Sebastian. An iconographic study: From painting to film

This article aims to show a first approximation which allows a better door understanding of the iconography of St Sebastian.Firstly, it will be considered what literary sources such as Passio refers about him.Secondly, this thesis will analyze the evolution of the iconography of this military saint BMX Forks until Contemporary art, taking into acco

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